Cesi's Substitution
The substitution system uses 4 letters. With: $x = \frac{\pi}{7}$, $c = \cos(x)$ and $s = \sin(x)$ They are: two squares of side lengths $1$ and $2-c-s$; a rectangle with sides $c+s$ and $2-c-s$: and a right triangle with legs $c$ and $s$. The substitution is indicated in the figure. Up to our knowledge, this was the first example of a substitution where the tiles occur in infinitely many orientations. Obviously, the substitution is not primitive.